Eye Box

Eye Box is a boss summoned by using the Soul of the Brain Titan, dropped by Brain Freeze. It will flip over 4 times in an attempt to aim its laser at you, and then will immediately shoot it. If he shoots the ground he will launch up into the air and be stunned for a moment. If he touches you before he shoots his laser, he will crush you. You have to shoot him in the eye to kill him.

Loot
Soul of the Eye Titan

Eye Box Trophy

Trivia
This is the third boss in a series of Titan Souls themed bosses. The one in question is Eye Cube.