Lemon Juiced!

'Lemon Juiced!' is a debuff inflicted by being near a Lemon Grenade when it explodes. While this debuff is in effect it covers most of the screens with ichor-yellow blobs that restrict vision severely and weakens your defense significantly, so that you would die to a Demon (not Red Devil) in two hits while wearing solar armor and at 500 HP. A Red Devil would just kill you if you had this debuff.