Defense Reduction

Defense Reduction is a mechanic that reduces defense. For example, if the player has 10% defense reduction and 100 defense, their defense will be 40 instead of 50(65 instead of 75 for expert mode). If an enemy has this the same thing happens. A Dereduct Potion can give a effect to the player that will make it so that every enemy that hits the player gets 5% defense reduction- this can be useful when the player is trying to speedrun bosses. However enemies can also do this to the player, such as the The Eyebomination in master mode.

List of items that allow Defense Reduction
Dereduct Potion